Cantaloupes have hard rinds that encase tender, orange fruit that hold an explosion of flavor and sweetness Plant in full sun in rich well draining soil. Beware of frost as Cantaloupes are susceptible. Cantaloupes, like honeydew, prefer warm soil and regular waterings to keep soil moist. Try to avoid getting stems and leaves wet to protect from mildews. Vines will produce both male and female flowers. Attracting a variety of pollinators is the key to having a large harvest. In colder climates removes flowers within 50 days of your first frost to ensure the ripening of fruit already on the vine.